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For example, myopia also known as short-sightedness or near-sightedness, has become a serious public health problem worldwide. The number of individuals Cutivate Lotion (Fluticasone Propionate Lotion)- Multum myopia has reached nearly 2 billion worldwide, which includes 277 million individuals with high myopia.

Due to the limited retention time of the drug in the conjunctival sac and low bioavailability, a nano-carrier DDS should be developed to load topical low-concentration atropine. The drug may achieve sustained release and improve the curative effect, which has potential value for the control of myopia. The penetration and delivery of drugs is particularly difficult under the complex and multiple physiological ocular barriers. Traditional drug preparations, such as eye drops, have a good therapeutic effect do topic anterior eye diseases, but there are some shortcomings, such as low bioavailability, frequent drug use, poor permeability.

Intravitreal injection of drugs overcomes the ocular barrier for posterior eye diseases and achieves a therapeutic effect, but it has a high risk of various complications and adverse reactions which have brought great challenges to the treatment of diseases.

Therefore, research and development of new DDSs are needed to better deliver drugs to the eyes and prolong the duration of drugs in the eyes.

Scientists have actively studied a variety of nanocarrier Cutivate Lotion (Fluticasone Propionate Lotion)- Multum, such as liposomes, nanoemulsions, nanoparticles, nano-suspensions and nanomicelles, which show excellent delivery potential in in vitro and in vivo animal models, and prolong the retention blood and sex in the eye, suggesting that nano-carrier DDSs are a good application prospect in ocular drug therapy approaches fungal have potential value for further clinical development.

The authors would like to acknowledge financial support from the National Natural Science Foundation of China (No. XLYC1807082), Shenyang Young and Middle-aged Science and Cutivate Lotion (Fluticasone Propionate Lotion)- Multum Innovation Talent Support Program (grant number RC190146).

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